AMINOGUANIDINE

Reported in the January/February issue of Medical Spa Magazine and listed in the TOP TEN Advancements in Anti-Aging Medicine 2002: "Anti-AGEs for Anti-aging: New research suggests that blood pressure drugs called ACE inhibitors, which help diabetics to lower their risk of developing complications, could be used to develop drugs that delay the effects of aging. Part of the reason why diabetics tend to age faster than non-diabetics is that their high-blood sugar levels encourages the body to produce complex proteins called advanced glycation end products (AGEs). These proteins interfere with cell functioning, accumulate in skin making it look wrinkly, and stiffen blood vessels. Now researchers at the Baker Institute in Melbourne, Australia have found that ACE inhibitors appear to exert their anti-aging effects by preventing the build-up of AGEs." Zed Laboratories has for years been formulating with aminoguanidine, an Anti-AGE ingredient. Aminoguanidine prevents the buildup of advanced glycation end products. It works by helping to prevent the advanced glycation end-products from attaching to the collagen fibrils in the skin. By preventing the A.G.E from collecting on the fibrils, aminoguanidine helps in keeping the skin soft and supple.

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